Grapefruit originated in Asia, but the tree has long been established in India, Japan, North America and the Mediterranean Basin. It is cultivated mainly for its edible fruit. It has always been reputed as being moisturizing and cleansing for skin. The active principles it contains, such as carbohydrates, amino acids and fruit acids, are responsible for its moisturizing and cleansing action, while the flavenoids normalize the permeability and increase the resistance of capillaries. This synergy is what produces its purifying effect.